Characterization of the lipid content ofToxoplasma gondiirhoptries
- 1 February 1991
- journal article
- research article
- Published by Cambridge University Press (CUP) in Parasitology
- Vol. 102 (3) , 367-370
- https://doi.org/10.1017/s0031182000064313
Abstract
Quantitative and qualitative analysis of lipids has been performed on a rhoptry fraction purified fromToxoplasma gondiitachyzoites. The lipid to protein ratio was estimated to be 0·26. The cholesterol to phospholipid ratio was unusually high at 1·48. Phosphatidylcholine was the major phospholipid; phosphatidylserine, phosphatidylinositol and sphingomyelin were absent whereas significant amounts of phosphatidic acid and lysophospholipids were found. This pelicular composition could be related to functional involvement of the organelle in host-cell invasion.Keywords
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