Drug-eluting stents: caution and concerns for long-term outcome
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- 1 September 2004
- journal article
- review article
- Published by Wolters Kluwer Health in Coronary Artery Disease
- Vol. 15 (6) , 313-318
- https://doi.org/10.1097/00019501-200409000-00003
Abstract
Recent publications on drug-eluting stents (DES) report a significant reduction in restenosis rates as compared to bare metal stents in patients mostly with single vessel disease. We have recently observed however, late stent thrombosis following CYPHERTM DES implantation. The patient developed a hypersensitivity reaction around stent struts limited to the polymer with aneurysmal dilatation and extensive inflammation of the arterial wall in the absence of vascular healing. This incidence promotes a cautionary view and perhaps supports the use of DES only in high-risk patients.Keywords
This publication has 13 references indexed in Scilit:
- Pathological Mechanisms of Fatal Late Coronary Stent Thrombosis in HumansCirculation, 2003
- Sirolimus-eluting stents for treatment of patients with long atherosclerotic lesions in small coronary arteries: double-blind, randomised controlled trial (E-SIRIUS)The Lancet, 2003
- Toxicity of methyl methacrylate in dentistryInternational Dental Journal, 2003
- Sirolimus-Eluting Stent Implanted in Human Coronary Artery for 16 MonthsCirculation, 2003
- Sirolimus-induced leukocytoclastic vasculitisTransplantation, 2002
- Clinical and laboratory-based methods in the diagnosis of natural rubber latex allergyJournal of Allergy and Clinical Immunology, 2002
- Twenty-eight-day efficacy and phamacokinetics of the sirolimus-eluting stentCoronary Artery Disease, 2002
- First Clinical Experience With a Paclitaxel Derivate–Eluting Polymer Stent System Implantation for In-Stent RestenosisCirculation, 2002
- Pathological Analysis of Local Delivery of Paclitaxel Via a Polymer-Coated StentCirculation, 2001
- Coronary stent coatingsCoronary Artery Disease, 1994