Dimere Pyrazinsteroid‐Alkaloide aus marinen Organismen: eine Herausforderung bei der Isolierung, der Synthese und der Erforschung ihrer biologischen Wirkung
- 15 March 1996
- journal article
- highlight
- Published by Wiley in Angewandte Chemie
- Vol. 108 (6) , 667-671
- https://doi.org/10.1002/ange.19961080607
Abstract
Nahezu eine Tonne mariner Röhrenwürmer mußte verarbeitet werden, um das erste Cephalostatin, 1, in Milligramm‐Mengen zu erhalten. Es gehört zu einer inzwischen dreißig Mitglieder umfassenden Familie von hochcytotoxischen dimeren Steroiden, zu denen nun auch chemische Zugänge gefunden wurden. magnified imageKeywords
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