Transmitter release from frog motor nerve terminals depends on motor unit size

Abstract
The success of a motor nerve terminal to compete for synaptic connections1,2 or the ability of an axon to maintain sprouts3 may depend on the support each terminal receives from its soma, presumably in the form of some substance(s) synthesized there. The support received by each terminal may depend on the total number of terminals, i.e., maintained by that soma, i.e., motor unit size. When motor unit size was decreased [in Rana pipiens], transmitter release from the terminals was markedly enhanced. The extent of support from the soma may influence the effectiveness of synaptic transmission.