Binding of bullous pemphigoid and pemphigus vulgaris sera to SCaBER cell line in an ELISA
- 1 January 1989
- journal article
- research article
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 120 (1) , 59-70
- https://doi.org/10.1111/j.1365-2133.1989.tb07766.x
Abstract
Specific antibodies present in the sera of patients with bullous pemphigoid or pemphigus vulgaris were detected in an enzyme-linked immunosorbent assay (ELISA) employing a squamous carcinoma cell line, SCaBER, as substrate. Bullous pemphigoid sera bound preferentially to permeabilized cells, suggesting that the antigens are largely intracellular. The assay may prove to be a useful addition to current methods of detecting circulating antibodies in these patients.This publication has 28 references indexed in Scilit:
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