Factors to consider in the development of generic bioanalytical high-performance liquid chromatographic–mass spectrometric methods to support drug discovery

This publication has 9 references indexed in Scilit:

• In vivo pharmacokinetic screening in cassette dosing experiments: the use of on-line prospekt® liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry technology in drug discovery
  Rapid Communications in Mass Spectrometry, 1998
• Cassette dosing: rapid in vivo assessment of pharmacokinetics
  Pharmaceutical Science & Technology Today, 1998
• Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations
  Analytical Chemistry, 1998
• A direct technique for the simultaneous determination of 10 drug candidates in plasma by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry interfaced to a prospekt solid-phase extraction system
  Journal of Pharmaceutical and Biomedical Analysis, 1997
• Simultaneous Pharmacokinetic Screening of a Mixture of Compounds in the Dog Using API LC/MS/MS Analysis for Increased Throughput
  Journal of Medicinal Chemistry, 1997
• The Simultaneous Determination of Mixtures of Drug Candidates by Liquid Chromatography/Atmospheric Pressure Chemical Ionization Mass Spectrometry as anIn Vivo Drug Screening Procedure
  Rapid Communications in Mass Spectrometry, 1997
• Quantitation of SR 27417 in human plasma using electrospray liquid chromatography-tandem mass spectrometry: A study of ion suppression
  Journal of the American Society for Mass Spectrometry, 1996
• Effect of organic solvent modifier and nature of solute on the performance of bonded silica reversed-phase columns for the analysis of strongly basic compounds by high-performance liquid chromatography
  Journal of Chromatography A, 1996
• Investigations of the electrospray interface for liquid chromatography/mass spectrometry
  Analytical Chemistry, 1990