Quantitative Testing and its Usefulness in the Evaluation of Therapy in Neurological Diseases

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Abstract
Clinical neurologists and neurosurgeons are beginning to realize the usefulness of quantitative testing batteries to augment the qualitative measurements of the standard neurological examination in evaluating treatments for neurological diseases. This paper briefly reviews the literature on the subject, defines what is meant by a clinical quantitative neurological test, discusses the advantages of quantitative testing, considers some essential ingredients in constructing a quantitative testing system, and describes the battery of tests which is being used currently by the authors. A sample of patients from a recent study of the efficacy of thalamotomy in Parkinson’s disease is used to develop an example illustrating the usefulness of quantitative testing.

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