Structural basis for the inhibitory efficacy of efavirenz (DMP‐266), MSC194 and PNU142721 towards the HIV‐1 RT K103N mutant
Open Access
- 14 March 2002
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 269 (6) , 1670-1677
- https://doi.org/10.1046/j.1432-1327.2002.02811.x
Abstract
The K103N substitution is a frequently observed HIV‐1 RT mutation in patients who do not respond to combination‐therapy. The drugs Efavirenz, MSC194 and PNU142721 belong to the recent generation of N...Keywords
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