Erythrocyte contents of electrolytes (Na, K, Mg, Zn) in healthy male controls and offspring to established hypertensive patients: A follow-up study

1 January 1983

journal article
research article
Published by Taylor & Francis in Scandinavian Journal of Clinical and Laboratory Investigation

Vol. 43 (4) , 317-322
https://doi.org/10.1080/00365518309168264

Abstract

Erythrocyte Na, K, Zn and Mg were measured in 56 male offspring to essential hypertensive patients and compared with 46 matched controls. The same parameters were measured again 4-6 mo. apart in 31 offspring and 8 controls. Intracellular Na was significantly higher in offspring (P < 0.001). There was a highly significant correlation between the 2 intraindividual measurements of intracellular Na, K and Zn but not for Mg. Na in erythrocytes is probably an indicator of the activity of the Na-pump and could possibly be used as a genetic marker in the future investigations of individuals with heredity for severe, essential hypertension.

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