Cutaneous histologic features in Ehlers-Danlos syndrome: study of 21 patients
- 1 January 1979
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 115 (1) , 40-42
- https://doi.org/10.1001/archderm.115.1.40
Abstract
Skin biopsy specimens from 21 patients with Ehlers-Danlos syndrome (EDS) were compared with controls. With 2 exceptions, the appearance of the dermal collagen and elastic tissue as seen in the 2 groups was indistinguishable. One example of type 4 EDS contained a dermis composed of fibers that resembled actinically damaged elastic tissue. The single example of type 6 EDS contained particularly thin collagen fibers. The dermal thickness of specimens of EDS was similar to that of controls, although the abnormal specimen of type 4 EDS was also abnormally thin. Since the other 2 biopsy specimens of type 4 appeared to be within the range of normal, there may be heterogeneity in this form of EDS.This publication has 1 reference indexed in Scilit:
- Inheritance of Ehlers-Danlos type IV syndrome.Journal of Medical Genetics, 1977