In vivo brain imaging using a portable 39?gram two-photon fluorescence microendoscope
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- 1 September 2005
- journal article
- research article
- Published by Optica Publishing Group in Optics Letters
- Vol. 30 (17) , 2272-2274
- https://doi.org/10.1364/ol.30.002272
Abstract
We introduce a compact two-photon fluorescence microendoscope based on a compound gradient refractive index endoscope probe, a DC micromotor for remote adjustment of the image plane, and a flexible photonic bandgap fiber for near distortion-free delivery of ultrashort excitation pulses. The imaging head has a mass of only and provides micrometer-scale resolution. We used portable two-photon microendoscopy to visualize hippocampal blood vessels in the brains of live mice.
Keywords
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