The Production and Study of an Acute Nicotinic Acid Deficiency in the Calf
- 1 June 1955
- journal article
- research article
- Published by Elsevier in Journal of Nutrition
- Vol. 56 (2) , 303-310
- https://doi.org/10.1093/jn/56.2.303
Abstract
Using a low-tryptophan diet, we have produced and described a nicotinic acid deficiency in the young calf. Symptoms exhibited by the 4 deficient animals were a loss of appetite, severe scouring, dehydration, weakness and sudden death by the second or third day on the deficient diet. There is a marked and rapid improvement in deficient animals following administration of nicotinic acid.Keywords
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