Cardiovascular Changes of the Burned Dog Following the Infusion of Intravenous Solutions

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Abstract
Cardiovascular responses of the burned dog to infusions of dextrose-saline, dextran, plasma and gelatin have been studied using changes in cardiac output as well as in plasma volume as a measure of therapeutic effectiveness. The experimental results demonstrate that restoration of plasma volume does not necessarily indicate good restoration of cardiac output, nor does restoration of cardiac output necessarily indicate restoration of plasma volume. Of the infusions studied, plasma and dextran appear to be equally effective, dextrose-saline least effective and gelatin intermediate.

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