Abstract
Reviews evidence regarding the efficacy of stimulant medications in treating aggression and antisocial behavior in externalizing youngsters, particularly those with attention-deficit hyperactivity disorder (ADHD). Despite claims that stimulant medication is not efficacious with respect to aggression, recent investigations with behavioral observation methodologies in large-group settings have revealed clinically significant reductions of aggressive behavior with stimulant treatment. Furthermore, among youngsters with attentional problems, both aggressive and nonaggressive subgroups show a positive response to such medication. Discussion focuses on the need for multimodality interventions with externalizing children.