A prospective randomized study with mineral oil and oral lavage solution for treatment of faecal impaction in children
- 1 October 1993
- journal article
- clinical trial
- Published by Wiley in Alimentary Pharmacology & Therapeutics
- Vol. 7 (5) , 523-529
- https://doi.org/10.1111/j.1365-2036.1993.tb00128.x
Abstract
Faecal impaction with or without encopresis is a very common problem. We performed a randomized, open-label, prospective study to compare the efficacy and acceptability of the treatment of faecal impaction using either mineral oil or pineapple-flavoured isotonic intestinal lavage solution containing polyethylene glycol-3350 (Colyte). Thirty-six patients over 2 years of age were randomized to receive either mineral oil or flavoured lavage solution. The dose of mineral oil was 2 to 8 tablespoons twice a day for two days (17 patients--Group I) and of lavage solution was 20 ml/kg/h for 4 hours on two consecutive days (19 patients--Group II). The patients were assessed for the presence of abdominal faecal masses, presence and consistency of rectal mass, perineal soiling before and two days after either of the randomly assigned treatment. The patients and parents were asked regarding the compliance with treatment, side-effects, number of bowel movements after treatment and willingness to try similar treatment if faecal impaction recurred. Patients in the lavage group had more frequent bowel movements, and showed more effective clearance of abdominal and rectal lumps (P < 0.01) at the time of repeat examination at two days. However, they had some vomiting and were less compliant (P < 0.01) when compared to mineral oil patients. We conclude that balanced lavage solution effectively relieves faecal impaction, however, compliance with its use is poorer than that with mineral oil.Keywords
This publication has 19 references indexed in Scilit:
- Intestinal button implantation for obstipation and fecal impaction in childrenJournal of Pediatric Surgery, 1992
- Safety, efficacy, and tolerance of intestinal lavage in pediatric patients undergoing diagnostic colonoscopyThe Journal of Pediatrics, 1991
- Comparison of a new sulfate-free polyethylene glycol electrolyte lavage solution versus a standard solution for colonoscopy cleansingGastrointestinal Endoscopy, 1990
- Fecal ImpactionNew England Journal of Medicine, 1989
- Size Exclusion Chromatographic Determination of PEG 3350 in Human Plasma and UrineAnalytical Letters, 1987
- Abnormal defecation dynamics in chronically constipated children with encopresisThe Journal of Pediatrics, 1986
- Gastrointestinal transit time, frequency of defecation, and anorectal manometry in healthy and constipated childrenThe Journal of Pediatrics, 1985
- Abnormal anal sphincter response in chronically constipated childrenThe Journal of Pediatrics, 1982
- Lubricant Versus Laxative in the Treatment of Chronic Functional Constipation of ChildrenJournal of Pediatric Gastroenterology and Nutrition, 1982
- Diagnosis and management in children with severe and protracted constipation and obstipationThe Journal of Pediatrics, 1963