THE CORPUS LUTEUM-PITUITARY RELATIONSHIP: ON THE REPORTS THAT OXYTOCIN STIMULATES THE SECRETION OF LUTEOTROPHIN11
- 1 July 1960
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 67 (1) , 122-125
- https://doi.org/10.1210/endo-67-1-122
Abstract
Injections of oxytocin, vasopressin or saline were made under a variety of conditions into separate groups of adult cycling female rats. Only 8 prolonged cycles (out of a total of 162), bearing no specific relation to oxytocin treatment, were observed during or following treatment. Lactating rats, deprived of their litters and subjected to uterine trauma on the 5th or 7th day postpartum, almost uniformly formed deciduomata, regardless of oxytocin treatment; when litters were removed on day 2, and the uterus traumatized on day 6, 50% formed deciduomata, regardless of oxytocin treatment. In the light of these and other results the theory that oxytocin stimulates LTH secretion was considered to be invalid.Keywords
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