Questioning the Role of Checkpoint Kinase 2 in the p53 DNA Damage Response

This publication has 56 references indexed in Scilit:

• The Chk2 Tumor Suppressor Is Not Required for p53 Responses in Human Cancer Cells
  Published by Elsevier ,2003
• Checkpoint Kinase 2 (Chk2) Monomers or Dimers Phosphorylate Cdc25C after DNA Damage Regardless of Threonine 68 Phosphorylation
  Journal of Biological Chemistry, 2002
• PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2
  Nature Cell Biology, 2002
• Determination of Substrate Motifs for Human Chk1 and hCds1/Chk2 by the Oriented Peptide Library Approach
  Journal of Biological Chemistry, 2002
• The evolution of diverse biological responses to DNA damage: insights from yeast and p53
  Nature Cell Biology, 2001
• Critical roles for the serine 20, but not the serine 15, phosphorylation site and for the polyproline domain in regulating p53 turnover
  Biochemical Journal, 2001
• Functional impact of concomitant versus alternative defects in the Chk2-p53 tumour suppressor pathway
  Oncogene, 2001
• A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase
  Current Biology, 1999
• Regulation of p53 stability by Mdm2
  Nature, 1997
• Mdm2 promotes the rapid degradation of p53
  Nature, 1997