Domain Fishing: a first step in protein comparative modelling
Open Access
- 1 August 2002
- journal article
- research article
- Published by Oxford University Press (OUP) in Bioinformatics
- Vol. 18 (8) , 1141-1142
- https://doi.org/10.1093/bioinformatics/18.8.1141
Abstract
Summary: To optimize the search for structural templates in protein comparative modelling, the query sequence is split into domains. The initial list of templates for each domain, extracted from PFAM plus PDB and SCOP, is then ranked according to sequence identity (%ID), coverage and resolution. If %ID is less than 30, secondary structure matching is used to filter out false templates. Availability: http://www.bmm.icnet.uk/~3djigsaw/dom_fish Contact: b.contreras-moreira@cancer.org.uk paul.bates@cancer.org.ukKeywords
This publication has 1 reference indexed in Scilit:
- Database of homology‐derived protein structures and the structural meaning of sequence alignmentProteins-Structure Function and Bioinformatics, 1991