RESULTS OF PREFRONTAL LOBECTOMY ON ACQUIRED AND ON ACQUIRING CORRECT CONDITIONED DIFFERENTIAL RESPONSES WITH AUDITORY, GENERAL CUTANEOUS AND OPTIC STIMULI

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Abstract
With one exception extirpation of both prefrontal areas produced no permanent effect on acquiring or on acquired correct conditioned differential responses elicited from somewhat similar tests with auditory, general cutaneous and optic stimuli. Correct conditioned differential reflexes were also obtained from both groups of dogs after prefrontal lobectomy from sound and general cutaneous stimuli when the positive and negative tests were alternated 4 to 6 times with intervals of 3 secs. between tests. After making due allowances for individual differences for certain tests and that the avg. dog had more difficulty in responding correctly to differential tests based on rate of a given analyser than on its various components, it is apparent that 2 of 5 dogs, which were not tested until after prefrontal lobectomy, required more tests than normal dogs to respond correctly with the 1 and 3 sec. sound tests and 1 dog was unable to acquire the same in the time allotted for the tests. The most promising of the 2d group of prefrontal lobectomized dogs did not acquire correct responses to a more complicated sound differential test.

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