Coeliac disease in monozygotic twin girls. Synchronous presentation.
- 1 September 1984
- Vol. 25 (9) , 1009-1012
- https://doi.org/10.1136/gut.25.9.1009
Abstract
A pair of monozygotic twin girls with coeliac disease is reported. The diagnosis was made on clinical and biochemical evidence of malabsorption, characteristic histological findings, and clinical, biochemical, and histological response to gluten elimination. Monozygosity was established on finding a single placenta at birth, exact similarity of physical appearance, similar blood group, and histocompatibility antigens, and negative reaction in mixed lymphocyte culture. This is one of six well documented cases of coeliac disease in monozygotic twins and may throw light on the importance of genetic and environmental factors in the causation and expression of the disease.Keywords
This publication has 15 references indexed in Scilit:
- PERORAL ENDOSCOPIC DUODENAL BIOPSY IN INFANTS AND CHILDRENActa Paediatrica, 1983
- Celiac disease in monozygous twin boysDigestive Diseases and Sciences, 1982
- Coeliac disease in identical twin infantsPostgraduate Medical Journal, 1981
- COELIAC DISEASE AND INFANT FEEDING PRACTICESThe Lancet, 1981
- Gluten Sensitive Enteropathy in Spain: Genetic and Environmental FactorsPublished by Springer Nature ,1981
- Coeliac disease in identical twins.Archives of Disease in Childhood, 1979
- HLA-DW3 ASSOCIATED WITH CŒLIAC DISEASEThe Lancet, 1976
- A family study of coeliac disease.Journal of Medical Genetics, 1975
- Discordance for childhood coeliac disease in monozygotic twinsGut, 1973
- Predominance of histocompatibility antigen HL-A8 in patients with gluten-sensitive enteropathyJournal of Clinical Investigation, 1972