LYSOSOMAL ENZYMES IN THE LYMPHOCYTES AND GRANULOCYTES OF PATIENTS WITH MULTIPLE SCLEROSIS

Abstract
The activities of 3 lysosomal enzymes were measured in the lymphocytes and granulocytes of patients with multiple sclerosis and of controls. The activity of acid phosphatase was increased in the granulocytes and that of .beta.-glucuronidase in the lymphocytes of MS patients in remission, as compared to those in relapse. No marked increases were observed in the activity of acid proteinase. A number of lysosomal enzymes in both lymphocytes and granulocytes can apparently be activated during demyelinating processes for reasons unknown at the moment.
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