Adenosquamous and squamous carcinomas of the duodenum are exceedingly rare lesions, only 5 cases, 3 of the former and 2 of the latter, having been reported in the literature. Three of the growths were peripapillary, and the others were localized in the suprapapillary segment of the duodenum. One of these involved the common bile duct by extension. The purpose of this communication is to review the essential features of these cases and to record an additional example of adenosquamous carcinoma of the peripapillary portion of the duodenum. REPORT OF A CASE H. C., a white man aged 49 years, entered the Elk County General Hospital, Ridgway, Pa., on Feb. 24, 1932, with jaundice, fever and moderately severe epigastric pain of short duration. Roentgenograms showed what was interpreted as a defect, probably neoplastic, of the pyloric portion of the stomach. The symptoms subsided, and the patient returned to work at the