Adreno-leukodystrophy
- 1 May 1974
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 30 (5) , 406-408
- https://doi.org/10.1001/archneur.1974.00490350064011
Abstract
Ultrastructural observations of an adrenal biopsy specimen from an 11-year-old boy with adreno-leukodystrophy showed that adrenocortical cells contained cytoplasmic accumulations of lamellar material. Each lamella consisted of two parallel, electron-dense 25 Angstrom leaflets separated by a variable 20 A to 70 A space. Rows of glycogen and a clear space often surrounded this material. Similar accumulations were also present in the Schwann cell cytoplasm of many of the myelinated nerve fibers in the adrenal capsule. These findings represent a possible morphologic link between the endocrine and nervous systems in this disease.Keywords
This publication has 1 reference indexed in Scilit:
- Adrenocortical Atrophy and Diffuse Cerebral SclerosisArchives of Disease in Childhood, 1971