Studies on organic fluorine compounds. XLIII. The ene reaction of hexafluoroacetone.

Publisher Website
Google Scholar
Abstract
The reaction of hexafluoroacetone with phenyl-substituted allyl compounds was found to give the ene products. Thus, allylbenzene gave 1, 1, 1-trifluoro-5-phenyl-2-(trifluoromethyl) pent-4-en-2-ol. Allyl phenyl ether and thioether gave the corresponding ene products. The product from the latter cyclized to 5-phenylthio-2, 2-bis (trifluoromethyl) tetrahydrofuran. N-Allyl-N-methylaniline reacted with the ketone to give the 4-(1, 1, 1, 3, 3, 3-hexafluoro-2-hydroxy-2-propyl) derivative via the Friedel-Crafts reaction, and this compound further reacted in the ene reaction to give unusual products.

This publication has 0 references indexed in Scilit: