Patterns of Perfusion-Weighted Imaging in Patients With Carotid Artery Occlusive Disease

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Abstract
CAROTID ARTERY stenosis or occlusion is responsible for a significant proportion of transient ischemic attacks (TIAs) and strokes. The relative importance of hemodynamic factors as opposed to embolic mechanisms in the pathogenesis of TIAs and strokes in these patients remains unresolved. Hypoperfusion was the most common explanation for brain ischemia 50 years ago. In the last 2 decades, emphasis has switched to embolism as the main mechanism of brain infarcts not only in anterior but also in posterior circulation.1 More recently, Caplan and Hennerici2 have posited the idea that both mechanisms often coexist and are complementary in patients who had an ischemic stroke.

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