Identification of the Gross cell surface antigen associated with murine leukemia virus-infected cells

1 August 1977

journal article
research article
Published by American Society for Microbiology in Journal of Virology

Vol. 23 (2) , 315-322
https://doi.org/10.1128/jvi.23.2.315-322.1977

Abstract

The Gross cell surface antigen (GCSA) is produced by cells that are either exogenously infected with murine leukemia virus (MuLV) or are expressing endogenous MuLV genomes. In immune precipitation assays, GCSA was resolved into two serologically distinct 85,000- and 95,000-dalton viral proteins. These antigenic components are glycosylated forms of the polyprotein precursors of the MuLV internal structural proteins.

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