Inhibiting Cell Division in Escherichia coli Has Little If Any Effect on Gene Expression
Open Access
- 1 February 2004
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 186 (3) , 880-884
- https://doi.org/10.1128/jb.186.3.880-884.2004
Abstract
DNA microarrays were used to compare gene expression in dividing and nondividing (filamentous) cultures of Escherichia coli . Although cells from these cultures differed profoundly in morphology, their gene expression profiles were nearly identical. These results extend previous evidence that there is no division checkpoint in E. coli , and progression through the cell cycle is not regulated by the transcription of different genes during different parts of the cell cycle.Keywords
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