Identification of Aquaporin 4 inhibitors using in vitro and in silico methods
- 1 January 2009
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry
- Vol. 17 (1) , 411-417
- https://doi.org/10.1016/j.bmc.2007.12.040
Abstract
No abstract availableKeywords
Funding Information
- Takeda Science Foundation
- Ministry of Education, Culture, Sports, Science and Technology
This publication has 48 references indexed in Scilit:
- Identification of arylsulfonamides as Aquaporin 4 inhibitorsBioorganic & Medicinal Chemistry Letters, 2007
- Comparative efficacy of HgCl2with candidate aquaporin‐1 inhibitors DMSO, gold, TEA+and acetazolamideFEBS Letters, 2006
- Three distinct roles of aquaporin-4 in brain function revealed by knockout miceBiochimica et Biophysica Acta (BBA) - Biomembranes, 2006
- Implications of the Aquaporin-4 Structure on Array Formation and Cell AdhesionJournal of Molecular Biology, 2006
- Sulforaphane enhances aquaporin-4 expression and decreases cerebral edema following traumatic brain injuryJournal of Neuroscience Research, 2005
- Inhibitors of type I MetAPs containing pyridine-2-carboxylic acid thiazol-2-ylamide. Part 1: SAR studies on the determination of the key scaffoldBioorganic & Medicinal Chemistry Letters, 2005
- Pregnancy‐induced up‐regulation of aquaporin‐4 protein in brain and its role in eclampsiaThe FASEB Journal, 2004
- Conjugation of poor inhibitors with surface binding groups: a strategy to improve inhibitionElectronic supplementary information (ESI) available: experimental details and UV-Vis titration data. See http://www.rsc.org/suppdata/cc/b3/b305179j/Chemical Communications, 2003
- Triptans in MigraineDrugs, 2000
- Functional expression from cloned cDNAs of glutamate receptor species responsive to kainate and quisqualateFEBS Letters, 1990