Central nervous system involvement in patients with acquired immune deficiency syndrome (AIDS)
- 29 January 2009
- journal article
- review article
- Published by Hindawi Limited in Acta Neurologica Scandinavica
- Vol. 71 (5) , 337-353
- https://doi.org/10.1111/j.1600-0404.1985.tb03211.x
Abstract
CNS involvement occurred in 28 of 121 patients with acquired immune deficiency syndrome (AIDS). The major risk factor in this AIDS population was i.v. drug abuse (64%). A neurologic symptom or disability was the principal reason for hospitalization in 16 cases (57%). Three patients had primary lymphoma of the brain and the remainder had opportunistic infections. Patients with focal neurological features usually had toxoplasmosis. Progressive headache and meningeal signs occurred with cryptococcosis. A progressive subacute dementia was probably due to cytomegalovirus. Other infections included atypical mycobacteria, candida, herpes zoster and possible progressive multifocal leukoencephalopathy.Keywords
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