Abstract
Progressive changes within the organs of adult Phormia regina infected with Octosporea muscaedomesticae are discussed. As early as postinocu-lation days 11-15 the epithelium of the posterior part of the proximal intestine may be reduced to shapeless pathogen-filled masses and the diseases fly dies. In some diseased flies that live for more than 16 days the infection may reach other parts of the enteron. Lethality of the disease in Musca domestica is also considered.

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