Differentiation of 19S and 7S Complement Fixing Antibodies in Primary Versus Recrudescent Typhus by Either Ethanethiol or Heat.
- 1 May 1965
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 119 (1) , 291-297
- https://doi.org/10.3181/00379727-119-30161
Abstract
Summary The CF test can be modified so as to permit the differentiation of 19S and 7S antibodies in primary and secondary typhus infections. The 19S CF antibodies are markedly inhibited by the sulfhydryl compound ethanethiol and to a lesser degree by 60° C inactivation of the sera, The 7S CF antibodies are not inhibited by either of these procedures. The technic described may have application to the clinical and epidemiological investigation of other infectious diseases and may prove useful as a tool in studies of the immune globulins.Keywords
This publication has 2 references indexed in Scilit:
- THE FORMATION OF MACROGLOBULIN ANTIBODIES. I. STUDIES ON ADULT HUMANS*Journal of Clinical Investigation, 1962
- Unusual Sedimentation and Sulfhydryl Sensitivity of Certain Isohemagglutinins and Skin-Sensitizing Antibody.Experimental Biology and Medicine, 1962