Min-protein oscillations inEscherichia coliwith spontaneous formation of two-stranded filaments in a three-dimensional stochastic reaction-diffusion model
- 13 February 2006
- journal article
- research article
- Published by American Physical Society (APS) in Physical Review E
- Vol. 73 (2) , 021904
- https://doi.org/10.1103/physreve.73.021904
Abstract
We introduce a three-dimensional stochastic reaction-diffusion model to describe MinD/MinE dynamical structures in Escherichia coli. This model spontaneously generates pole-to-pole oscillations of the membrane-associated MinD proteins, MinE ring, as well as filaments of the membrane-associated MinD proteins. Experimental data suggest MinD filaments are two-stranded. In order to model them we assume that each membrane-associated MinD protein can form up to three bonds with adjacent membrane-associated MinD molecules and that MinE induced hydrolysis strongly depends on the number of bonds MinD has established.Keywords
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