FINE STRUCTURES OF THE SPLEEN IN HEREDITARY ELLIPTOCYTOSIS
- 1 September 1976
- journal article
- research article
- Published by Wiley in Acta Pathologica Japonica
- Vol. 26 (5) , 533-542
- https://doi.org/10.1111/j.1440-1827.1976.tb00510.x
Abstract
Light microscopic and EM studies of the spleen and liver from a patient with hereditary elliptocytosis were reported. Characteristic findings are congestion of the cordal space, diminished variation of the erythrocyte shape in the cord, relatively empty sinuses and erythrophagocytosis by the cordal macrophages. The same basic defect of the red cell membrane as was documented in hereditary spherocytosis might be a possible explanation for the pathogenesis of this rare hemolytic anemia.Keywords
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