Infusions of Donor Leukocytes to Treat Epstein-Barr Virus-Associated Lymphoproliferative Disorders after Allogeneic Bone Marrow Transplantation
Open Access
- 28 April 1994
- journal article
- case report
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 330 (17) , 1185-1191
- https://doi.org/10.1056/nejm199404283301703
Abstract
Lymphoma associated with Epstein-Barr virus (EBV) is a complication of bone marrow transplantation that responds poorly to standard forms of therapy. The lymphoma is usually of donor origin. We hypothesized that treatment with infusions of donor leukocytes, which contain cytotoxic T cells presensitized to EBV, might be an effective treatment.Keywords
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