5-Methylcytosine content in Gryllotalpa fossor (Orthoptera)
- 1 February 1992
- journal article
- Published by Canadian Science Publishing in Genome
- Vol. 35 (1) , 163-166
- https://doi.org/10.1139/g92-026
Abstract
The MspI-HpaII digestion patterns of Gryllotalpa fossor (Scudder) DNA indicated the methylation of internal cytosine in the sequence 5′ -CCGG-3′. The amount of 5-methylcytosine (5mC) was estimated by HPLC analysis to be about 0.6–0.8%, which constitutes approximately 3% of the total cytosine in the genome. This is the first example of a non-mammalian animal with appreciable levels of 5mC.Key words: insect genome, 5-methylcytosine, DNA methylation.Keywords
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