Expression of Vimentin and Epidermal Growth Factor Receptor In Effusions From Patients With Breast Cancer; Correlation With Oestrogen and Progesterone Receptor Status
- 1 April 1993
- journal article
- Published by Wiley in Cytopathology
- Vol. 4 (2) , 91-98
- https://doi.org/10.1111/j.1365-2303.1993.tb00520.x
Abstract
The epidermal growth factor receptor (EGFr) status and the vimentin (V) status of malignant cells in pleural fluids from patients with breast cancer were determined using an immunoperoxidase labelling technique. The results were correlated with the oestrogen receptor (ER) and the progesterone receptor (PR) status of the primary tumour and with disease-free survival time of the patient. A negative correlation between EGFr and V status and hormone receptor status was found. The longest mean survival time occurred in patients with negative EGFr and V status and positive hormone receptor (ER and PR) status. The shortest mean survival time occurred in patients with positive EGFr and V and negative ER and PR status.Keywords
This publication has 8 references indexed in Scilit:
- Expression of epidermal growth factor receptor in breast carcinoma.Journal of Clinical Pathology, 1990
- Immunocytochemical Determination of Epidermal Growth Factor Receptor with Monoclonal EGFR1 Antibody in Primary Breast Cancer PatientsOncology, 1990
- Growth factor expression in normal, benign, and malignant breast tissueBMJ, 1988
- Vimentin and p53 expression on epidermal growth factor receptor-positive, oestrogen receptor-negative breast carcinomasBritish Journal of Cancer, 1988
- The prognostic value and relationships of patient characteristics, estrogen and progestin receptors, and site of relapse in primary breast cancerCancer, 1988
- Presence of epidermal growth factor receptor as an indicator of poor prognosis in patients with breast cancer.Journal of Clinical Pathology, 1985
- Progesterone Receptors as a Prognostic Factor in Stage II Breast CancerNew England Journal of Medicine, 1983
- In vitro synthesis of the major lens membrane protein.Proceedings of the National Academy of Sciences, 1980