An audiological investigation of osteogenesis imperfecta

Abstract
The auditory status of osteogenesis imperfecta [a genetic disorder] patients was obtained and compared to that of otosclerosis patients. Biphasic acoustic reflex responses [reported in otosclerosis patients] were not obtained in osteogenesis imperfecta patients. Apparently the conductive hearing loss associated with osteogenesis imperfecta differed from that in otosclerosis. High resting tympanic membrane admittance values were obtained in osteogenesis imperfecta patients suggesting lack of tympanic membrane stiffness as a sign of this syndrome.

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