The treatment of tinnitus with oral anticonvulsants
- 1 January 1979
- journal article
- research article
- Published by Cambridge University Press (CUP) in The Journal of Laryngology & Otology
- Vol. 93 (2) , 111-122
- https://doi.org/10.1017/s0022215100086837
Abstract
The oral anticonvulsants carbamazepine and diphenylhydantoin were tested against i.v. lignocaine for their effectiveness in relieving tinnitus. Patients were given a full audiological examination to determine the nature of tinnitus and hearing loss; disequilibrium and vertigo were noted. Audiometric changes and side effects due to carbamazepine and diphenylhydantoin were studied. Tinnitus was relieved by the drugs, but returned on withdrawal of the drugs. Apparently oral anticonvulsant therapy is a viable alternative treatment for tinnitus, and newer anticonvulsants may be more effective, with fewer side effects.This publication has 11 references indexed in Scilit:
- The use of intravenous lignocaine in the diagnosis and treatment of tinnitusThe Journal of Laryngology & Otology, 1978
- Priming for audiogenic seizures in BALB/c mice as a function of stimulus exposure duration and intensityExperimental Neurology, 1975
- Further experiments on vestibular compensationThe Laryngoscope, 1972
- Neuronal hyperactivity in experimental trigeminal deafferentationJournal of Neurosurgery, 1971
- Some Possible Mechanisms of Action of Antiepileptic Drugs*Pharmacopsychiatry, 1970
- Diphenylhydantoin and intracellular sodium concentrationNeurology, 1969
- Chronic Deafferentation of Human Spinal Cord NeuronsJournal of Neurosurgery, 1968
- Spontaneous spike discharges from single units in the cochlear nucleus after destruction of the cochleaExperimental Neurology, 1966
- Effect of procaine on electrical properties of squid axon membraneAmerican Journal of Physiology-Legacy Content, 1959