Psychological Distress and Sexuality in a Group of Women Attending a Menopause Clinic

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Abstract
Fifty-seven women attending a menopause clinic were evaluated for psychological, social, and sexual aspects of postmenopause through a self-administered questionnaire given at 6-month intervals. The women were put on either estradiol valerate/cyproterone acetate or conjugated estrogen/medroxyprogesterone acetate combinations or no treatment. After 12 months, the Psychiatric Symptom Index global and anxiety scores improved significantly in both treatment groups but not in the control group. The depression score improved in both treated groups but did not reach statistical significance in the estradiol valerate/cyproterone acetate group. Cognition and hostility scores improved in all groups during the trial but the improvement in the treated groups was not different from that observed in the control group. Health parameters remained constant and stress did not change significantly. Sexual parameters remained unchanged. This study shows that hormonal replacement therapy plays a role in the improvement of psychological aspects of menopause.

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