Iodine-125, a tracer in cell biology: physical properties and biological aspects
- 1 July 1970
- journal article
- Published by IOP Publishing in Physics in Medicine & Biology
- Vol. 15 (3) , 447-456
- https://doi.org/10.1088/0031-9155/15/3/005
Abstract
Some essential physical properties of the transmutation of iodine-125 are discussed and the range of its electrons calculated. Its suitability for autoradiographs is compared with that of tritium. The dose distribution around a point source and the dose absorbed by a cell nucleus labelled with 125I and 3H are calculated. It is suggested that the biological toxicity of iodine-125 is not only due to energy deposition of its radiation but also to molecular fragmentation caused by charge transfer in consequence of the Auger effect.Keywords
This publication has 22 references indexed in Scilit:
- Effect of 32P decay upon RNA transcription by a radiation-sensitive strain of Escherichia coliJournal of Molecular Biology, 1968
- Measurement of the L+M+…/K electron capture ratio in the decay of 125INuclear Physics, 1966
- 125I-DU (5-IODO-2′-deoxyuridine) in autoradiographic studies of cell proliferationExperimental Cell Research, 1966
- Biological Efficiency of P 32 Transmutation in Diploid Saccharomyces cerevisiaeRadiation Research, 1964
- Improved resolution in autoradiography with radioiodine using the extranuclear electron radiation from 125IBiochimica et Biophysica Acta, 1963
- Formation of Fragment Ions from CH3Te125 and C2H5Te125 Following the Nuclear Decays of CH3I125 and C2H5I125The Journal of Chemical Physics, 1963
- Resolution and image spread in autoradiographs of tritium-labeled cellsThe International Journal of Applied Radiation and Isotopes, 1959
- Ionization following internal conversion in xenonProceedings of the Royal Society of London. Series A. Mathematical and Physical Sciences, 1957
- Decay ofPhysical Review B, 1952