Cell therapy for ischaemic heart disease

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Abstract
Over the past decades, substantial advances in risk factor modification, pharmacological treatment, and revascularisation therapy have significantly reduced the mortality of ischaemic heart disease (IHD). Nevertheless, IHD remains a leading cause of morbidity and mortality. Cell therapy is currently being investigated as a potential treatment modality for patients with IHD. Preclinical studies suggested that cell therapy may have a favourable effect on tissue perfusion and contractile performance by promoting vascularisation and myocyte formation. Following these encouraging preclinical results, cell therapy has rapidly been introduced into the clinical setting.

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