Nucleosome core particles suppress the thermal untwisting of core DNA and adjacent linker DNA.
- 1 July 1985
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 82 (14) , 4653-4657
- https://doi.org/10.1073/pnas.82.14.4653
Abstract
Covalently closed circular DNA undergoes temperature-dependent change in helical twist. Nucleosome core particles [from chicken erythrocytes] were reconstituted onto closed circular DNA and the thermal untwisting of the DNA was measured as a function of nucleosome density. The DNA associated with the nucleosome core particle does not alter its twist when the temperature is varied between 4.degree. C and 37.degree. C, and the length of DNA prevented from thermal untwisting includes the linker as well as the core DNA.This publication has 35 references indexed in Scilit:
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