• 1 January 1980
    • journal article
    • research article
    • Vol. 26  (8) , 62-65
Abstract
Patients (136) with chronic lesions of the esophagus and stomach were observed dynamically for 5 yr using fibroesophagogastroscopy. Twelve patients showed esophageal cancer development (7 of 86 patients with chronic esophagitis and 5 of 15 patients with leukoplakia). A high incidence of leukoplakial transition into cancer allows its being referred to as an obligate precancer of the esophagus. Atrophic esophagitis presents the background against which leukoplakia arises.

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