Demonstration of 3-methoxytyrosine in the urine of melanoma patients

Open Access

1 January 1975

journal article
research article
Published by Medical Journals Sweden AB in Acta Dermato-Venereologica

Vol. 56 (1) , 27-31
https://doi.org/10.2340/00015555562731

Abstract

With the aid of gas chromatography and mass spectrometry a metabolite of dopa, 3-methoxytyrosine, has been demonstrated in the urine of 2 patients with melanoma metastases, the amounts excreted being 4.0 mg and 8.5 mg/24 hours, respectively. 3-Methoxytyrosine could not with certainty be identified in the urines of two normal subjects.