Streptonigrin and related compounds. I. Some 2‐phenyl‐ and 2,2‐pyridylquinoline‐5,8‐diones
- 1 August 1975
- journal article
- research article
- Published by Wiley in Journal of Heterocyclic Chemistry
- Vol. 12 (4) , 725-730
- https://doi.org/10.1002/jhet.5570120422
Abstract
Methods for the synthesis of 6‐amino‐7‐methoxy‐ and 7‐amino‐6‐methoxy‐2,2‐pyridylquinoline‐ 5,8‐diones and the corresponding 2‐phenylquinoline‐5,8‐diones are described. The 6‐aminoquinone system was generated by direct amination with sodium azide and the 7‐aminoquinone system via the novel 6‐hydroxy‐7‐nitroquinone intermediates. The basic skeleton was derived by the application of the Friedlander quinoline synthesis.Keywords
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