Abstract
Coe virus dissociated readily from infected DMB cells in tissue culture, but 25% to 50% of virus was still intracellular at time of maximum cytopathic effect. The virus was relatively stable when exposed to repeated freezing and thawing, and to storage at -70[degree]C, 4[degree]C, and room temperature. At 37[degree]C, 90% of the virus was inactivated within 3 days, and less than 1% of the particles were infectious after 20 days. Coe virus is rapidly inactivated at 50[degree]C, but a few particles survive for 30 minutes at this temperature. Coe virus is ether resistant and resistant to inactivation at pH 6.0 to 9.0.

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