Isolation of 2-(3‘-Bromo-4‘-hydroxyphenol)ethanamine from the New Zealand Ascidian Cnemidocarpa bicornuta

Abstract
From the ascidian Cnemidocarpa bicornuta, 2-(3‘-bromo-4‘-hydroxyphenol)ethanamine (3‘-bromotyramine) (1) has been isolated along with the previously reported sponge metabolite, 1,3-dimethylisoguanine. The structure of 1 was confirmed by synthesis.