GPCRDB: information system for G protein-coupled receptors
Top Cited Papers
Open Access
- 2 November 2010
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 39 (Database) , D309-D319
- https://doi.org/10.1093/nar/gkq1009
Abstract
The GPCRDB is a Molecular Class-Specific Information System (MCSIS) that collects, combines, validates and disseminates large amounts of heterogeneous data on G protein-coupled receptors (GPCRs). The GPCRDB contains experimental data on sequences, ligand-binding constants, mutations and oligomers, as well as many different types of computationally derived data such as multiple sequence alignments and homology models. The GPCRDB provides access to the data via a number of different access methods. It offers visualization and analysis tools, and a number of query systems. The data is updated automatically on a monthly basis. The GPCRDB can be found online at http://www.gpcr.org/7tm/ .Keywords
This publication has 44 references indexed in Scilit:
- Utopia documents: linking scholarly literature with research dataBioinformatics, 2010
- GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge BaseBioinformatics, 2010
- Jalview Version 2—a multiple sequence alignment editor and analysis workbenchBioinformatics, 2009
- Improving physical realism, stereochemistry, and side‐chain accuracy in homology modeling: Four approaches that performed well in CASP8Proteins-Structure Function and Bioinformatics, 2009
- GenBankNucleic Acids Research, 2007
- GLIDA: GPCR ligand database for chemical genomics drug discovery database and tools updateNucleic Acids Research, 2007
- Integration of biological networks and gene expression data using CytoscapeNature Protocols, 2007
- How many drug targets are there?Nature Reviews Drug Discovery, 2006
- Taverna: a tool for building and running workflows of servicesNucleic Acids Research, 2006
- The Protein Data BankNucleic Acids Research, 2000