Stereoselective Synthesis of Neu5Acα(2→5)Neu5Gc: The Building Block of Oligo/Poly(→5-OglycolylNeu5Gcα2→) Chains in Sea Urchin Egg Cell Surface Glycoprotein
- 18 September 2002
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 67 (21) , 7565-7568
- https://doi.org/10.1021/jo025988p
Abstract
[[abstract]]The synthesis of a sialic acid dimer derivative, Neu5Acalpha(2-->5)Neu5Gc, is described. The synthetic strategy is based on the use of allyl alcohol to achieve an exclusive alpha-sialylation product. The allyloxy group is also a latent glycolic acid that provides the subsequent coupling with neuraminate with minimal protection-deprotection manipulations[[fileno]]2010318010054[[department]]化學This publication has 11 references indexed in Scilit:
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