Effect of Ergometric Exercise on the Activity in the Serum of Creatine Phosphokinase, Glutamate-Oxaloacetate Transminase and Aldolase in Rheumatoid Arthritis

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Abstract
Summary An ergometric exertion test was performed on 15 female rheumatoid arthritics with marked muscular atrophy, on 15 female arthritics without/with slight muscular atrophy and on 15 healthy female nurses. Minimal CPK activity appeared after exertion in 17 cases out of 30 among both rheumatoid groups, and in 6 out of 13 among the control group. Immediately following exertion there appeared a slight, but significant rise in GOT activity in both rheumatoid groups; in the control group the rise was insignificant. Aldolase activity remained at a significantly high level in both rheumatoid groups 60 minutes after exertion. In the control group the rise was insignificant. There were no significant differences between the female rheumatoid arthritics with marked muscular atrophy and without/with slight muscular atrophy with regard to urinary excretion of creatine and creatinine or to increase of serum GOT and aldolase activity after muscular exertion.

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